Publication Name	World Journal of Transplantation
Manuscript ID	115114
Country	United States

Category	Transplantation
Manuscript Type	Case Report
Article Title	Gemcitabine-sirolimus synergy associated thrombotic microangiopathy in a renal transplant recipient with mesenteric leiomyosarcoma: A case report
Manuscript Source	Invited Manuscript
All Author List	Vishaal Motla, Usman Baig, Laura Mulloy, Talal Nakkar, Shameem Beigh and Imran Gani
Funding Agency and Grant Number
Corresponding Author	Imran Gani, Associate Professor, Department of Nephrology, Hypertension and Transplant Medicine, Wellstar MCG Health, Augusta University, 1120 15th Steet, Augusta, GA 30912, United States. igani@augusta.edu
Key Words	Mesenteric leiomyosarcoma; Gemcitabine; Sirolimus; Thrombotic microangiopathy; Renal transplantation; Case report
Core Tip	Thrombotic microangiopathy represents a rare yet serious complication in renal transplant patients, potentially causing rapid loss of allograft function. Various medications, including gemcitabine and sirolimus, have been implicated in its pathogenesis. Even with discontinuation of causative agents and anticomplement therapy, allograft function may progressively worsen.
Citation	Motla V, Baig U, Mulloy L, Nakkar T, Beigh S, Gani I. Gemcitabine-sirolimus synergy associated thrombotic microangiopathy in a renal transplant recipient with mesenteric leiomyosarcoma: A case report. World J Transplant 2026; In press

Received	2025-10-13 08:34
Peer-Review Started	2025-10-13 08:34
First Decision by Editorial Office Director	2025-11-10 07:06
Return for Revision	2025-11-10 07:06
Revised	2025-11-22 20:03
Publication Fee Transferred
Second Decision by Editor	2026-01-28 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-28 13:42
Articles in Press	2026-01-28 13:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
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