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Publication Name World Journal of Gastroenterology
Manuscript ID 115131
Country China
Category Medicine, Research & Experimental
Manuscript Type Review
Article Title Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance
Manuscript Source Unsolicited Manuscript
All Author List Jia-Qi Yu, Shen-Jie Yu, Ya-Hui He, Yu-Zhe Xue, Xiao-Fang Yu, Wei Chen, Ling-Yu Hu, Xiao-Fang Fan, Zhao-Feng Gao, Hong-Kun Zhou, Xiao-Rong Liu, Xue-Song He and Xiao-Guang Wang
Funding Agency and Grant Number
Funding Agency Grant Number
Key R&D Program of Zhejiang Province 2024C03062
Project of the Bureau of Science and Technology of Jiaxing City 2024AZ30002
Natural Science Foundation of Zhejiang Province LBY23H200001
Project of Zhejiang Provincial Medical and Health Research 2023KY1212
Starlit South Lake Leading Elite Program 2023A400006
Corresponding Author Xue-Song He, PhD, Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Jiaxing University, No. 397 Huancheng North Road, Jiaxing 314000, Zhejiang Province, China. hexuesong2007@163.com
Key Words Plant-derived chemical compounds; Pancreatic cancer; Drug resistance mechanisms; Reversal of resistance; Cancer
Core Tip This review summarizes recent research on the role of plant-derived compounds in overcoming drug resistance in pancreatic cancer. It provides insights into the mechanisms of resistance and highlights the potential of plant-based compounds as alternative therapeutic strategies. Considering the limitations of current therapies and the growing issue of drug resistance, plant-derived compounds offer a promising direction for enhancing treatment outcomes. This review aims to inform future research and contribute to the development of more effective, safer, and patient-friendly treatment options for pancreatic cancer.
Citation Yu JQ, Yu SJ, He YH, Xue YZ, Yu XF, Chen W, Hu LY, Fan XF, Gao ZF, Zhou HK, Liu XR, He XS, Wang XG. Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance. World J Gastroenterol 2026; In press
Received
2025-10-14 06:00
Peer-Review Started
2025-10-14 06:00
First Decision by Editorial Office Director
2025-11-05 09:11
Return for Revision
2025-11-05 09:11
Revised
2025-11-11 02:25
Publication Fee Transferred
2025-11-12 02:06
Second Decision by Editor
2026-01-08 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-08 09:44
Articles in Press
2026-01-08 09:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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