Publication Name	World Journal of Medical Genetics
Manuscript ID	115237
Country	Argentina

Category	Genetics & Heredity
Manuscript Type	Review
Article Title	Mineralocorticoid receptor genetics: A scoping review
Manuscript Source	Invited Manuscript
All Author List	Sebastián Pedro Antonio Jaurretche, Clara Balañá and Renata Máxima Bascolo
Funding Agency and Grant Number
Corresponding Author	Sebastián Pedro Antonio Jaurretche, Professor, Uro-Onco-Nephrology and Transplant, Sanatorio Parque SA, Oroño 860, Rosario 2000, Santa Fe, Argentina. sebastianjaurretche5@gmail.com
Key Words	Mineralocorticoid receptor; Genetics; Nuclear receptor subfamily 3 gene; Genotype; Phenotype
Core Tip	The mineralocorticoid receptor (MR) has emerged as a multifaceted regulator extending beyond electrolyte and blood pressure control to roles in cardiovascular, renal, metabolic, and neural physiology. In addition, MR is expressed in various tissues and organs in humans. However, the genetic dimension of MR function remains underexplored and, the genotype-phenotype correlation is only known for a few mutations of the MR gene. The genetics of the MR determine its functionality; therefore, a better understanding of it can be the basis of the personalized medicine approach.
Citation	Jaurretche SPA, Balañá C, Bascolo RM. Mineralocorticoid receptor genetics: A scoping review. World J Med Genet 2026; In press

Received	2025-10-14 05:02
Peer-Review Started	2025-10-14 05:02
First Decision by Editorial Office Director	2025-10-17 07:23
Return for Revision	2025-10-17 07:23
Revised	2025-11-20 10:19
Publication Fee Transferred
Second Decision by Editor	2026-02-11 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-11 06:19
Articles in Press	2026-02-11 06:19
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3184 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com