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Publication Name World Journal of Nephrology
Manuscript ID 115357
Country Italy
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Gut-kidney axis: Dysbiosis and renal disease
Manuscript Source Invited Manuscript
All Author List Maurizio Salvadori and Giuseppina Rosso
Funding Agency and Grant Number
Corresponding Author Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Tuscany, Italy. maurizio.salvadori1@gmail.com
Key Words Gut-kidney axis; Chronic kidney disease; Gut microbiota; Dysbiosis; Uremic toxins; Prebiotics; Synbiotics
Core Tip It has been recently established an axis among gut, liver and kidney. In conditions of gut microbiota modifications, otherwise called dysbiosis, this alteration can favor uremic toxins (UTs) in blood circulation and the progression of chronic kidney disease (CKD). The principal questions are which exactly is the cross talk between gut, liver and kidney, whether a specific microbiota is linked to CKD and in generating UTs, whether gut dysbiosis favors the progression of CKD. Finally, which are the possible therapeutical measures for such condition.
Citation Salvadori M, Rosso G. Gut-kidney axis: Dysbiosis and renal disease. World J Nephrol 2026; In press
Received
2025-10-21 05:30
Peer-Review Started
2025-10-21 05:30
First Decision by Editorial Office Director
2025-11-04 09:36
Return for Revision
2025-11-04 09:36
Revised
2025-11-25 03:14
Publication Fee Transferred
Second Decision by Editor
2026-01-14 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-14 09:13
Articles in Press
2026-01-14 09:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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