Publication Name	World Journal of Diabetes
Manuscript ID	115435
Country	China

Category	Methodology
Manuscript Type	Editorial
Article Title	From fatty liver indices to the Zhejiang University index: Re-shaping risk stratification of metabolic liver disease in diabetes
Manuscript Source	Invited Manuscript
All Author List	Mostafa M Gouda
Funding Agency and Grant Number
Corresponding Author	Mostafa M Gouda, PhD, Professor, College of Biosystems Engineering and Food Science, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou 310027, Zhejiang Province, China. mostafa-gouda@zju.edu.cn
Key Words	Metabolic dysfunction-associated; Type 2 diabetes mellitus; Zhejiang University index; Fatty liver index; Hepatic steatosis index; Non-invasive diagnostics; Risk stratification
Core Tip	Early identification of metabolic dysfunction-associated steatotic liver disease (MASLD) in diabetes requires reliable and easily applicable tools. The Zhejiang University index (ZJU index) combines metabolic and hepatic parameters, such as body mass index, fasting glucose, triglycerides, and enzyme ratios, into a simple score derived from routine clinical data. Unlike traditional indices such as fatty liver index and hepatic steatosis index, the ZJU index demonstrates superior accuracy for detecting MASLD and correlates with systemic complications, including insulin resistance and sarcopenia. Its integration into electronic medical records enables automatic annual screening of patients with type 2 diabetes mellitus, providing a cost-effective, non-invasive approach for risk stratification and guiding timely preventive interventions.
Citation	Gouda MM. From fatty liver indices to the Zhejiang University index: Re-shaping risk stratification of metabolic liver disease in diabetes. World J Diabetes 2025; In press

Received	2025-10-16 11:14
Peer-Review Started	2025-10-20 00:30
To Make the First Decision
Return for Revision	2025-11-05 07:48
Revised	2025-11-08 02:07
Second Decision	2025-11-18 01:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-18 08:47
Articles in Press	2025-11-18 08:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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