Publication Name	World Journal of Hepatology
Manuscript ID	115456
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Systematic Reviews
Article Title	Correlation between non-alcoholic fatty liver disease and erectile dysfunction: A systematic narrative review
Manuscript Source	Invited Manuscript
All Author List	Yan-Fei He, Ning Bian, Huan-Zhi Wang, Xiao-Dong Hu, Jun-Qiang Liu, Shuang-Feng Lu, Ni Wu, Qin-Tong He and Hu-Ming Li
Funding Agency and Grant Number
Corresponding Author	Yan-Fei He, Associate Chief Physician, MD, Department of Health Management Center, The Sixth Medical Center, Chinese PLA General Hospital, No. 6 Fucheng Road, Haidian District, Beijing 100048, China. heyanfeilc@163.com
Key Words	Non-alcoholic fatty liver disease; Erectile dysfunction; Chronic liver diseases; Sexual dysfunction; Metabolic syndrome; Insulin resistance; Systematic review; Narrative synthesis
Core Tip	Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. It often occurs alongside metabolic disorders, such as obesity and type 2 diabetes. Erectile dysfunction (ED) is a common sexual health issue in men. However, there is limited high-quality evidence systematically examining the relationship between ED and NAFLD. This systematic narrative review summarizes the existing research and confirms that NAFLD is a significant risk factor for ED. The strength of this association depends on various factors, including age, insulin resistance, testosterone levels, and anxiety. This study provides evidence-based support for the early identification of ED risk in NAFLD patients, which is significant for advancing comprehensive metabolic interventions, both socially and clinically.
Citation	He YF, Bian N, Wang HZ, Hu XD, Liu JQ, Lu SF, Wu N, He QT, Li HM. Correlation between non-alcoholic fatty liver disease and erectile dysfunction: A systematic narrative review. World J Hepatol 2026; In press

Received	2025-10-17 13:34
Peer-Review Started	2025-10-17 13:34
First Decision by Editorial Office Director	2025-11-18 10:29
Return for Revision	2025-11-18 10:29
Revised	2025-11-23 17:02
Publication Fee Transferred
Second Decision by Editor	2026-02-05 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-05 08:11
Articles in Press	2026-02-05 08:11
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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