Publication Name	World Journal of Stem Cells
Manuscript ID	115482
Country	China

Category	Urology & Nephrology
Manuscript Type	Basic Study
Article Title	FOXP1 promotes the proliferation and self-renewal of spermatogonial stem cells via the nuclear factor kappa B pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Jin-Hua Wu, Feng Lin, Yan-Hua Wang, Jiang-Ping Xie, Shu-Lin Guo and Pei-Yan Liu
Funding Agency and Grant Number
Corresponding Author	Pei-Yan Liu, Department of Andrology, Ganzhou People’s Hospital of Jiangxi Province, No. 17 Hongqi Avenue, Ganzhou 341000, Jiangxi Province, China. lpygzsnxyxk@163.com
Key Words	Forkhead box P1; Spermatogonial stem cells; Proliferation; Self‑renewal; Nuclear factor kappa B pathway; Male infertility; Azoospermia; ETS variant gene 5; Promyelocytic leukemia zinc finger
Core Tip	Spermatogonial stem cells (SSCs) are the basis of spermatogenesis in mammals and can self-renew or differentiate into the various cell types in the germ cell lineage. SSC homeostasis dysregulation is closely associated with male infertility. This study revealed the role of forkhead box P1 in regulating the function of SSCs via the nuclear factor kappa B pathway, thus offering a basis for the diagnosis and treatment of male infertility.
Citation	Wu JH, Lin F, Wang YH, Xie JP, Guo SL, Liu PY. FOXP1 promotes the proliferation and self-renewal of spermatogonial stem cells via the nuclear factor kappa B pathway. World J Stem Cells 2026; In press

Received	2025-11-07 09:17
Peer-Review Started	2025-11-07 09:17
First Decision by Editorial Office Director	2025-11-28 07:47
Return for Revision	2025-11-28 07:47
Revised	2025-12-25 07:06
Publication Fee Transferred
Second Decision by Editor	2026-02-13 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-25 03:53
Articles in Press	2026-02-25 03:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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