Publication Name	World Journal of Stem Cells
Manuscript ID	115486
Country	China

Category	Obstetrics & Gynecology
Manuscript Type	Review
Article Title	Innovations in the treatment of endometrial diseases: Role of human umbilical cord mesenchymal stem cells and their exosomes
Manuscript Source	Unsolicited Manuscript
All Author List	He-Lin Wang, Shi-Dong Zhang, Ting Liu, Li-Mei Liu and Xiao-Yan Pan
Funding Agency and Grant Number	Funding Agency Grant Number Scientific and Technological Research Project of Jilin Province 20240305074YY Industrial Technology Research and Development Project of the Jilin Provincial Development and Reform Commission 2023C027-8
Corresponding Author	Xiao-Yan Pan, Professor, Center for Reproductive Medicine, Jilin Medical University, No. 5 Jilin Street, Fengman District, Jilin 132013, Jilin Province, China. pxy19790122@163.com
Key Words	Human umbilical cord mesenchymal stem cells; Exosomes; Endometrial regeneration; Endometrial diseases; Treatment
Core Tip	This review offers a critical analysis of human umbilical cord mesenchymal stem cell and exosome therapies for endometrial diseases. It synthesizes compelling mechanistic and clinical evidence while rigorously identifying the key translational roadblocks - standardization, clinical validation, and safety - that must be overcome to move from promising research to widespread clinical practice.
Citation	Wang HL, Zhang SD, Liu T, Liu LM, Pan XY. Innovations in the treatment of endometrial diseases: Role of human umbilical cord mesenchymal stem cells and their exosomes. World J Stem Cells 2026; In press

Received	2025-10-20 09:04
Peer-Review Started	2025-10-20 09:05
First Decision by Editorial Office Director	2025-11-18 07:40
Return for Revision	2025-11-18 07:40
Revised	2026-01-01 05:09
Publication Fee Transferred
Second Decision by Editor	2026-02-14 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-25 04:23
Articles in Press	2026-02-25 04:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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