Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	115497
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Controlled Trial
Article Title	Impact of early postoperative pain management strategies on complication rates in infants with biliary atresia after Kasai portoenterostomy
Manuscript Source	Unsolicited Manuscript
All Author List	Zhi-Jun Yan, Xiao-Hua Guo, Zi-Xia Huang, Jie Huang and Wen-Jie Liu
Funding Agency and Grant Number
Corresponding Author	Wen-Jie Liu, Associate Chief Physician, MD, Department of Anesthesiology, The Second Affiliated Hospital of University of South China, No. 30 Jiefang Road, Shigu District, Hengyang 421001, Hunan Province, China. wenjieliu96@163.com
Key Words	Pediatric biliary atresia; Kasai portoenterostomy; Postoperative pain; Multimodal analgesia; Complications
Core Tip	This study demonstrates that an early multimodal analgesia protocol, utilizing ultrasound-guided transversus abdominis plane block combined with patient-controlled intravenous analgesia, is superior to conventional on-demand opioid analgesia for infants after Kasai surgery. This approach not only provides superior and safer pain control but is also associated with reduced postoperative complications (particularly cholangitis and pulmonary infection), faster recovery, and significantly improved 6-month native liver survival.
Citation	Yan ZJ, Guo XH, Huang ZX, Huang J, Liu WJ. Impact of early postoperative pain management strategies on complication rates in infants with biliary atresia after Kasai portoenterostomy. World J Gastrointest Surg 2026; In press

Received	2025-11-07 09:30
Peer-Review Started	2025-11-07 09:30
First Decision by Editorial Office Director	2025-11-28 06:54
Return for Revision	2025-11-28 06:54
Revised	2025-12-12 15:57
Publication Fee Transferred	2025-12-18 14:35
Second Decision by Editor	2026-01-22 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-22 03:30
Articles in Press	2026-01-22 03:30
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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