Publication Name	Artificial Intelligence in Gastroenterology
Manuscript ID	115498
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Multimodal artificial intelligence integrates imaging, endoscopic, and omics data for intelligent decision-making in individualized gastrointestinal tumor treatment
Manuscript Source	Invited Manuscript
All Author List	Hui Nian, Yi-Bin Wu, Yu Bai, Zhi-Long Zhang, Xiao-Huang Tu, Qi-Zhi Liu, De-Hua Zhou and Qian-Cheng Du
Funding Agency and Grant Number	Funding Agency Grant Number Xuhui District Health Commission SHXH202214
Corresponding Author	Qian-Cheng Du, MD, Department of Thoracic Surgery, Shanghai Xuhui Central Hospital, No. 366 Longchuan North Road, Xuhui District, Shanghai 200031, China. duqc1991106@sina.com
Key Words	Multimodal artificial intelligence; Gastrointestinal tumors; Individualized therapy; Intelligent diagnosis; Treatment optimization; Prognostic prediction; Data fusion; Deep learning; Precision medicine
Core Tip	This review highlights that multimodal artificial intelligence (AI), by integrating imaging, endoscopic, and multi-omics data, is revolutionizing the intelligent decision-making process for individualized gastrointestinal tumor therapy. It enhances precision across the entire clinical spectrum-from improving early detection and accurate staging, to optimizing treatment planning and prognostic assessment. The key to its success lies in effectively addressing challenges related to data fusion, model interpretability, and multicenter validation. Ultimately, multimodal AI serves as a pivotal translational bridge, connecting complex data analysis with actionable clinical insights to advance precision oncology.
Citation	Nian H, Wu YB, Bai Y, Zhang ZL, Tu XH, Liu QZ, Zhou DH, Du QC. Multimodal artificial intelligence integrates imaging, endoscopic, and omics data for intelligent decision-making in individualized gastrointestinal tumor treatment. Artif Intell Gastroenterol 2025; In press

Received	2025-10-20 00:38
Peer-Review Started	2025-10-20 00:38
First Decision by Editorial Office Director	2025-10-27 09:25
Return for Revision	2025-10-27 09:25
Revised	2025-11-04 13:53
Publication Fee Transferred
Second Decision by Editor	2025-12-18 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-18 10:01
Articles in Press	2025-12-18 10:01
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2644-3236 (online)
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