Publication Name	World Journal of Cardiology
Manuscript ID	115528
Country	Kyrgyzstan

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Cohort Study
Article Title	Efficacy of nitroglycerin versus labetalol in hypertensive emergency among patients with a history of coronary artery disease
Manuscript Source	Unsolicited Manuscript
All Author List	Ahmed Jamal Chaudhary, Wasim Akbar Bhat, Affan Ul Haq, Haroon Ur Rashid, Irum Dad Khan, Mah Noor Dad Khan, Hafiz Muhammad Mubeen Nawaz, Sameer Ali and Muhammad Hamza Tariq
Funding Agency and Grant Number
Corresponding Author	Muhammad Hamza Tariq, MD, Department of Cardiology, International Medical University, Ankara Street 1/17, Bishkek 720052, Kyrgyzstan. muhammadhamzatariq103@gmail.com
Key Words	Hypertensive emergency; Coronary artery disease; Nitroglycerin; Labetalol; Blood pressure control; Cardiovascular outcomes
Core Tip	This retrospective study uniquely compares intravenous nitroglycerin and labetalol for managing hypertensive emergencies in a large South Asian cohort of patients with established coronary artery disease. Although labetalol achieved target blood pressure more rapidly, nitroglycerin provided greater magnitude of blood pressure reduction, significantly lower rates of bradycardia, smaller rises in cardiac biomarkers, shorter intensive care unit and hospital stays, and reduced 30-day readmissions. These findings highlight nitroglycerin’s potential advantages in ischemic contexts and support its preferential use in high-risk coronary artery disease patients within resource-constrained settings.
Citation	Chaudhary AJ, Bhat WA, Ul Haq A, Rashid HU, Khan ID, Khan MND, Nawaz HMM, Ali S, Tariq MH. Efficacy of nitroglycerin versus labetalol in hypertensive emergency among patients with a history of coronary artery disease. World J Cardiol 2025; In press

Received	2025-10-20 10:18
Peer-Review Started	2025-10-20 10:19
First Decision by Editorial Office Director	2025-10-30 09:15
Return for Revision	2025-10-30 09:15
Revised	2025-11-01 09:52
Publication Fee Transferred
Second Decision by Editor	2025-12-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-17 08:51
Articles in Press	2025-12-17 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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