Publication Name	World Journal of Virology
Manuscript ID	115626
Country	Tunisia

Category	Virology
Manuscript Type	Retrospective Cohort Study
Article Title	Cytomegalovirus reactivation risk after autologous hematopoietic stem cell transplantation: Results of a Tunisian study
Manuscript Source	Invited Manuscript
All Author List	Mouna Louiza Ben Moussa, Yasmine Chelbi, Rachid Kharrat, Rabeb Berred, Raihane Ben Lakhal, Manel Hamdoun and Olfa Bahri
Funding Agency and Grant Number
Corresponding Author	Mouna Louiza Ben Moussa, MD, Laboratory of Microbiology and Biochemistry, Aziza Othmana Hospital, Rue de la Kasbah, Tunis 1008, Tunisia. mounabenmoussa46@yahoo.fr
Key Words	Cytomegalovirus; Reactivation; Autologous hematopoietic stem cell transplantation; Preemptive therapy; Viral load monitoring
Core Tip	This retrospective cohort study analyzed cytomegalovirus (CMV) reactivation after autologous hematopoietic stem cell transplantation in 277 patients. CMV reactivation occurred in 6.1% of cases, often spontaneously resolving but occasionally leading to severe disease and death in patients with high viral loads. Initial and peak viral loads were significantly associated with treatment need, supporting viral quantification as a key decision tool. These findings emphasize the importance of systematic post-transplant CMV monitoring and early preemptive therapy to prevent progression to clinically significant CMV disease.
Citation	Ben Moussa ML, Chelbi Y, Kharrat R, Berred R, Ben Lakhal R, Hamdoun M, Bahri O. Cytomegalovirus reactivation risk after autologous hematopoietic stem cell transplantation: Results of a Tunisian study. World J Virol 2025; In press

Received	2025-10-21 05:43
Peer-Review Started	2025-10-21 05:45
First Decision by Editorial Office Director	2025-11-04 09:36
Return for Revision	2025-11-04 09:36
Revised	2025-11-14 16:37
Publication Fee Transferred
Second Decision by Editor	2025-12-08 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-08 03:22
Articles in Press	2025-12-08 03:22
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3249 (online)
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