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Publication Name World Journal of Gastroenterology
Manuscript ID 115649
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Lean type 2 diabetes mellitus is an independent predictor of mortality in primary biliary cholangitis
Manuscript Source Unsolicited Manuscript
All Author List Ting-Ting Yin, Hui-Ying Lin, Min Zhou, Jian-Wei Li, Qiu-Lan Mo, Hong-Jing Wang, Jie Chen, Hui-Ling Zhu, Yu-Ting Li, Meng-Yao Zheng and Jin-Hui Yang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82160106
Yunnan Provincial Department of Education Scientific Research Fund Project 2025J0270
Yunnan Provincial Science and Technology Department Science and Technology Program Project 202501AY070001-088
Corresponding Author Jin-Hui Yang, Chief Physician, Full Professor, Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, No. 374 Dianmian Avenue, Wuhua District, Kunming 650101, Yunnan Province, China. yangjinhui@kmmu.edu.cn
Key Words Diabetes mellitus; Lean body weight; Nutritional status; Primary biliary cholangitis; Prognosis
Core Tip Although the adverse prognostic implications of lean diabetes have been documented in various disease contexts, its specific impact on clinical outcomes and underlying mechanisms in primary biliary cholangitis patients remain largely unexplored. This study represents the first comprehensive investigation that systematically evaluates the detrimental effects of lean diabetes on primary biliary cholangitis patient prognosis and critically examines the synergistic interaction and cooperative enhancement mechanisms between diabetes and lean phenotype.
Citation Yin TT, Lin HY, Zhou M, Li JW, Mo QL, Wang HJ, Chen J, Zhu HL, Li YT, Zheng MY, Yang JH. Lean type 2 diabetes mellitus is an independent predictor of mortality in primary biliary cholangitis. World J of Gastroenterol 2026; In press
Received
2025-10-22 09:50
Peer-Review Started
2025-10-22 09:50
First Decision by Editorial Office Director
2025-12-03 10:23
Return for Revision
2025-12-03 10:23
Revised
2025-12-16 07:26
Publication Fee Transferred
2025-12-18 15:03
Second Decision by Editor
2026-01-28 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-28 07:55
Articles in Press
2026-01-28 07:55
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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