Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	115698
Country	China

Category	Surgery
Manuscript Type	Case Report
Article Title	Loop ileostomy-induced reversible nonalcoholic fatty liver disease in a rectal cancer patient: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Yong-Kang Liang, Ju-He Zhang, Song Liang, Shen-Wei Wu and Xue-Yi Feng
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research Fund of Bengbu Medical University No. 2024byzd288
Corresponding Author	Xue-Yi Feng, MD, PhD, Department of General Surgery, Lu’an Hospital of Anhui Medical University (Lu’an People’s Hospital of Anhui Province), No. 21 West Wanxi Road, Lu’an 237005, Anhui Province, China. fxy514270277@126.com
Key Words	Nonalcoholic fatty liver disease; Rectal cancer; Loop ileostomy; Glucagon-like peptide 1; Peptide YY(3-36); Case report
Core Tip	This case highlights a rare, reversible occurrence of nonalcoholic fatty liver disease following loop ileostomy in a rectal cancer patient. The temporal association between ileostomy, increased appetite, dyslipidemia, and fluctuations in glucagon-like peptide 1 and peptide YY(3-36) levels suggests a potential metabolic impact of ileostomy. These findings introduce a novel hypothesis linking gastrointestinal anatomical changes to hepatic lipid accumulation, warranting further mechanistic investigation.
Citation	Liang YK, Zhang JH, Liang S, Wu SW, Feng XY. Loop ileostomy-induced reversible nonalcoholic fatty liver disease in a rectal cancer patient: A case report and review of literature. World J Gastrointest Surg 2026; In press

Received	2025-10-24 06:49
Peer-Review Started	2025-10-24 06:49
First Decision by Editorial Office Director	2025-11-25 09:27
Return for Revision	2025-11-26 02:28
Revised	2025-12-04 10:32
Publication Fee Transferred	2025-12-05 10:13
Second Decision by Editor	2026-02-12 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-12 03:52
Articles in Press	2026-02-12 03:52
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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