Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	115719
Country	Brazil

Category	Surgery
Manuscript Type	Minireviews
Article Title	What does the surgeon need to know about microsatellite instability in gastric cancers?
Manuscript Source	Unsolicited Manuscript
All Author List	Paulo Pimentel de Assumpção, Geraldo Ishak, Paula Baraúna de Assumpção, Samir Mansour Moraes Casseb, João Felipe Acioli, Sérgio Augusto Antunes Ramos, Jéssica Manoelli Costa Silva, Kauê Sant'Ana Pereira Guimarães, Carolina Baraúna de Assumpção, Paulo Kassab and Paul Mansfield
Funding Agency and Grant Number
Corresponding Author	Paulo Pimentel de Assumpção, Director, MD, PhD, Professor, Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, R. dos Mundurucus, 4487 - Guamá, Belém - PA, 66073-000, Belém 66073-000, Pará, Brazil. assumpcaopp@gmail.com
Key Words	Gastric cancer; Microsatellite instability; Mismatch repair; Immunotherapy; Surgical oncology
Core Tip	This is an overview of the biological foundations, molecular mechanisms, diagnostic approaches, and clinical relevance of microsatellite instability in gastric cancer, emphasizing its role as a prognostic biomarker. The text also discusses therapeutic implications, including personalized surgical decision-making, treatment stratification, and the growing importance of integrating immunotherapy within multidisciplinary oncologic care.
Citation	de Assumpção PP, Ishak G, de Assumpção PB, Casseb SMM, Acioli JF, Ramos SAA, Silva JMC, Guimarães KSP, de Assumpção CB, Kassab P, Mansfield P. What does the surgeon need to know about microsatellite instability in gastric cancers? World J Gastrointest Oncol 2026; In press

Received	2025-10-24 08:09
Peer-Review Started	2025-10-24 08:09
First Decision by Editorial Office Director	2025-10-29 08:14
Return for Revision	2025-10-29 08:14
Revised	2025-11-06 14:28
Publication Fee Transferred	2025-12-26 12:25
Second Decision by Editor	2026-01-19 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-19 04:29
Articles in Press	2026-01-19 04:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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