Publication Name	World Journal of Gastroenterology
Manuscript ID	115821
Country	China

Category	Integrative & Complementary Medicine
Manuscript Type	Minireviews
Article Title	Mechanisms and therapeutic potential of traditional Chinese medicine for inflammatory bowel disease
Manuscript Source	Unsolicited Manuscript
All Author List	Si-Hui Zeng, Xiao-Yan Jiang, De-Rong Lin, Wei-Jian Zhang, Yu-Qi Wu, Lin Xu and Shao-Ju Guo
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82204994
Corresponding Author	Shao-Ju Guo, Department of Spleen and Stomach Diseases, Shenzhen Traditional Chinese Medicine Hospital, No. 1 Fuhua Road, Shenzhen 518000, Guangdong Province, China. gsjgsjgsj2024@163.com
Key Words	Traditional Chinese medicine; Inflammatory bowel disease; Mechanism; Inflammatory signalling pathways; Immune regulation; Gut microbiota; Intestinal barrier function; Multi-target therapy
Core Tip	Inflammatory bowel disease management faces limitations with conventional therapies. Traditional Chinese medicine (TCM) offers a holistic, multi-target therapeutic strategy. This minireview elucidates how TCM treats inflammatory bowel disease by synergistically modulating immunity, repairing the intestinal barrier, restoring gut microbiota, and regulating inflammatory pathways and autophagy, thereby accelerating the modernization and integration of TCM into global healthcare.
Citation	Zeng SH, Jiang XY, Lin DR, Zhang WJ, Wu YQ, Xu L, Guo SJ. Mechanisms and therapeutic potential of traditional Chinese medicine for inflammatory bowel disease. World J Gastroenterol 2026; In press

Received	2025-10-27 13:24
Peer-Review Started	2025-10-27 13:24
First Decision by Editorial Office Director	2025-11-25 09:27
Return for Revision	2025-11-25 09:27
Revised	2025-12-09 15:33
Publication Fee Transferred	2025-12-13 03:30
Second Decision by Editor	2026-01-16 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-16 07:50
Articles in Press	2026-01-16 07:50
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com