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Articles in Press
1/7/2026 5:02:06 AM | Browse: 3 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Development and validation of a risk prediction model for small intestinal mucosal injury in nonsteroidal anti-inflammatory drug users
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ning-Hui Zhao, Ling-Ran Zhao, Jia Yao, Ling-Yun Niu, Long-Jun Yang, Yu-Jia Lin and Mei Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| General Program of the National Natural Science Foundation of China |
No. 82472961 |
| Key Research and Development Projects of Hubei Province, China |
No. SCZ202111 |
| Research and Innovation Team Project for Scientific Breakthroughs at Shanxi Bethune Hospital |
No. 2024ZHANCHI06 |
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| Corresponding Author |
Mei Liu, Professor, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Road, Wuhan 430030, Hubei Province, China. fliumei@126.com |
| Key Words |
Small intestinal mucosal injury; Nonsteroidal anti-inflammatory drug; Capsule endoscopy; Risk factors; Prediction model |
| Core Tip |
This study identified advanced age, smoking, proton pump inhibitor use, elevated body mass index, high triglyceride, and low-density lipoprotein levels as independent risk factors for small intestinal mucosal injury in nonsteroidal anti-inflammatory drug users. A predictive nomogram was developed based on these factors. The model demonstrated good predictive accuracy, with an area under the curve of 0.775 in the derivation cohort and 0.797 in the validation cohort. This tool can facilitate early identification of high-risk individuals and guide clinical interventions to prevent small intestinal mucosal injury. |
| Citation |
Zhao NH, Zhao LR, Yao J, Niu LY, Yang LJ, Lin YJ, Liu M. Development and validation of a risk prediction model for small intestinal mucosal injury in nonsteroidal anti-inflammatory drug users. World J Gastrointest Surg 2026; In press |
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Received |
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2025-10-27 13:37 |
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Peer-Review Started |
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2025-10-27 13:41 |
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First Decision by Editorial Office Director |
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2025-11-19 10:00 |
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Return for Revision |
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2025-11-19 10:00 |
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Revised |
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2025-11-27 15:09 |
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Publication Fee Transferred |
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2025-11-29 12:24 |
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Second Decision by Editor |
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2026-01-07 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-07 05:02 |
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Articles in Press |
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2026-01-07 05:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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