Publication Name	World Journal of Psychiatry
Manuscript ID	115867
Country	China

Category	Psychiatry
Manuscript Type	Meta-Analysis
Article Title	Meta-analysis of dopaminergic-serotonergic modulation strategies for depressive symptoms in Parkinson’s disease
Manuscript Source	Unsolicited Manuscript
All Author List	Cheng-Cheng Li, Yan Zhou, Kai-Xia Chen, Li Zhang, Wen-Lie Gu and Hong Gu
Funding Agency and Grant Number
Corresponding Author	Hong Gu, Associate Chief Pharmacist, Department of Pharmacy, Jingjiang People’s Hospital Affiliated to Yangzhou University, No. 28 Zhongzhou Road, Taizhou 214500, Jiangsu Province, China. honggujj@163.com
Key Words	Parkinson’s disease; Depressive disorder; Dopaminergic agents; Selective serotonin reuptake inhibitors; Combination therapy
Core Tip	This meta-analysis of five studies discussed the clinical efficacy of dopaminergic agents combined with selective serotonin reuptake inhibitors in the treatment of Parkinson’s disease with depressive disorder. The results showed that the effective rate of depression improvement and the quality of life score of the combined treatment were higher, but there was no significant difference in motor function. These findings highlight the importance of combined therapy for Parkinson’s disease and depressive disorders.
Citation	Li CC, Zhou Y, Chen KX, Zhang L, Gu WL, Gu H. Meta-analysis of dopaminergic-serotonergic modulation strategies for depressive symptoms in Parkinson’s disease. World J Psychiatry 2026; In press

Received	2025-11-14 08:31
Peer-Review Started	2025-11-14 08:31
First Decision by Editorial Office Director	2025-12-03 07:10
Return for Revision	2025-12-03 07:10
Revised	2025-12-16 07:55
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-03 01:24
Articles in Press	2026-02-03 01:24
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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