Publication Name	World Journal of Gastroenterology
Manuscript ID	115876
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study
Manuscript Source	Unsolicited Manuscript
All Author List	Miao Duan, Qing-Zhou Kong, Xiu-Li Zuo, Xiao-Yun Yang and Yue-Yue Li
Funding Agency and Grant Number	Funding Agency Grant Number Fundamental Research Funds for the Central Universities 2022JC021 National Natural Science Foundation of China 82270570 National Natural Science Foundation of China 82070551 ECCM Program of Clinical Research Center of Shandong University 2021SDUCRCB003
Corresponding Author	Yue-Yue Li, MD, PhD, Professor, Department of Gastroenterology, Qilu Hospital of Shandong University, No. 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China. lyynqj@126.com
Key Words	Helicobacter pylori eradication; Quality measurement; Healthcare quality improvement; Medical education; Helicobacter pylori
Core Tip	A significant improvement in the effectiveness of Helicobacter pylori infection therapy was observed among gastroenterologists following a single structured training course, as demonstrated by this prospective, before-and-after, non-randomized interventional study based on real-world data. Following training, physicians achieved significantly higher eradication rates (58.6% vs 71.6% in intention-to-treat analysis) and improved therapy standardization. The intervention was particularly beneficial for less experienced physicians and those with historically lower success rates. These findings highlight that targeted professional education is a simple, effective strategy to improve clinical outcomes and standardize care in Helicobacter pylori eradication.
Citation	Duan M, Kong QZ, Zuo XL, Yang XY, Li YY. Optimizing Helicobacter pylori therapy through gastroenterologist education: A prospective interventional study. World J Gastroenterol 2025; In press

Received	2025-10-29 13:24
Peer-Review Started	2025-10-29 13:25
First Decision by Editorial Office Director	2025-12-02 10:07
Return for Revision	2025-12-02 10:07
Revised	2025-12-11 05:39
Publication Fee Transferred	2025-12-12 15:28
Second Decision by Editor	2025-12-31 02:31
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-31 06:16
Articles in Press	2025-12-31 06:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com