Publication Name	World Journal of Transplantation
Manuscript ID	115879
Country	Argentina

Category	Pathology
Manuscript Type	Editorial
Article Title	Multifaceted role of histopathology in liver transplantation for hepatocellular carcinoma: A narrative review towards precision prognosis
Manuscript Source	Invited Manuscript
All Author List	Marcelo Fabián Amante, María Fernanda Vargas Wille and María L Pestalardo
Funding Agency and Grant Number
Corresponding Author	Marcelo Fabián Amante, Department of División Patología, Hospital General de Agudos Cosme Argerich, Pi y Margall 480, Buenos Aires C1155AHA, Ciudad Autónoma de, Argentina. marcelofabianamante@gmail.com
Key Words	Hepatocellular carcinoma; Liver transplantation; Histopathology; Vascular invasion; Tumor differentiation; Prognostic stratification; Precision medicine
Core Tip	Histopathological assessment remains indispensable for liver transplantation in hepatocellular carcinoma, providing crucial information about tumor biology that imaging alone cannot capture. This editorial emphasizes how vascular invasion, tumor differentiation, and histologic subtyping critically refine prognostic stratification and guide individualized post-transplant management. By integrating standardized sampling with digital pathology and molecular profiling, pathology evolves from a diagnostic discipline into a predictive and decision-shaping science, optimizing organ allocation for hepatocellular carcinoma transplantation and improving long-term outcomes for patients.
Citation	Amante MF, Vargas Wille MF, Pestalardo ML. Multifaceted role of histopathology in liver transplantation for hepatocellular carcinoma: A narrative review towards precision prognosis. World J Transplant 2026; In press

Received	2025-10-28 06:39
Peer-Review Started	2025-10-28 06:39
First Decision by Editorial Office Director	2025-11-05 08:58
Return for Revision	2025-11-05 08:58
Revised	2025-11-19 12:48
Publication Fee Transferred
Second Decision by Editor	2026-02-03 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-03 09:33
Articles in Press	2026-02-03 09:33
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
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