Publication Name	World Journal of Experimental Medicine
Manuscript ID	115894
Country	Egypt

Category	Urology & Nephrology
Manuscript Type	Letter to the Editor
Article Title	Urinary infection in European guidelines 2025 vs microbiology culture results in the management of urinary infection
Manuscript Source	Invited Manuscript
All Author List	Mohamed Wishahi and Mohamed Badawy
Funding Agency and Grant Number
Corresponding Author	Mohamed Wishahi, Full Professor, MD, PhD, Department of Urology, Theodor Bilharz Research Institute, Embaba, Giza, Cairo 12411, Egypt. moh.weshahy@gmail.com
Key Words	Microbial communities; Urinary infection; Urine culture; Microbiome; Probiotics; Metagenomics; Antibiotic
Core Tip	The European Association of Urology guidelines 2025 for urinary infections (UIs) published new classification describing localized and systemic UIs. Patient’s Symptoms, clinical examinations, laboratory, and imaging investigation are required to set up the diagnosis. Localized UIs could be treated on an ambulatory basis, while systemic infection indicates hospitalization and monitoring. Urine culture would not reveal all bacterial community in urine. Second generation sequencing reveals bacterial community including dysbiosis and helper microbiota. Implementing the new guidelines would lead to personalized medicine, minimizing antibiotics use, avoid antibiotic resistance, and considering probiotics in treatment of localized infections.
Citation	Wishahi M, Badawy M. Urinary infection in European guidelines 2025 vs microbiology culture results in the management of urinary infection. World J Exp Med 2026; In press

Received	2025-10-29 02:34
Peer-Review Started	2025-10-29 02:34
First Decision by Editorial Office Director	2025-11-06 09:03
Return for Revision	2025-11-06 09:03
Revised	2025-11-11 15:13
Publication Fee Transferred
Second Decision by Editor	2026-01-21 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-21 06:41
Articles in Press	2026-01-21 06:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-315x (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com