| Category |
Urology & Nephrology |
| Manuscript Type |
Observational Study |
| Article Title |
Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rodrigo Daza Arnedo, Vicente Sánchez Polo, Jenniffer Benavides Garcia, Juan Felipe Gutiérrez, Enrique Ramos Clason, Daniel Domínguez, Giovany Mera Rebutti, Carlos Madrid Mancia, Rene Tabora López, Manuel Rocha Meza, Dany Tabora López, James J Muñoz Zambrano, Eduardo Lorca Herrera, Eliana Dina-Batlle, Michael Cieza Terrones, Thyago Proença de Moraes, Tomas Rodriguez Yánez, Washington Osorio, Alyi Arellano Cabeza and Jorge Rico-Fontalvo |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Jorge Rico-Fontalvo, Faculty of Medicine, Department of Nephrology, Simón Bolívar University of Barranquilla, 59th Street No. 59-65, Barranquilla 080002, Atlántico, Colombia. jorgericof@yahoo.com |
| Key Words |
Finerenone; Chronic kidney disease; Type 2 diabetes; Diabetic nephropathy; Albuminuria; Hyperkalemia |
| Core Tip |
In a real-world observational study of 347 Latin American patients with type 2 diabetes mellitus and chronic kidney disease finerenone demonstrated significant short-term benefits. After six months, treatment led to major reductions in the urinary albumin-creatinine ratio and blood pressure. This efficacy was achieved with very good tolerance; the estimated glomerular filtration rate remained stable, and serum potassium increases were minimal, highlighting a low risk of hyperkalemia. This study provides crucial real-world evidence supporting finerenone’s safety and effectiveness. |
| Citation |
Arnedo RD, Polo VS, Garcia JB, Gutiérrez JF, Clason ER, Domínguez D, Rebutti GM, Mancia CM, López RT, Meza MR, López DT, Zambrano JJM, Herrera EL, Dina-Batlle E, Terrones MC, de Moraes TP, Yánez TR, Osorio W, Cabeza AA, Rico-Fontalvo J. Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial. World J Nephrol 2026; In press |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |