Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	115972
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Mei-Lan Jiang, Jian-Ping Bao, Si-Cong Jiang and Fang-Gen Xu
Funding Agency and Grant Number	Funding Agency Grant Number Application for Key Discipline Construction Project of High Tech Hospital, First Affiliated Hospital of Nanchang University GX2D20247402
Corresponding Author	Fang-Gen Xu, MD, Department of Gastroenterology, Gaoxin Branch of the First Affiliated Hospital of Nanchang University, No. 7889 Changdong Avenue, High Tech Zone, Nanchang 330006, Jiangxi Province, China. 13607988780@163.com
Key Words	Severe acute pancreatitis; Early enteral nutrition; Delayed enteral nutrition; Mortality; Infectious complications; Gut barrier function
Core Tip	This prospective cohort study evaluated the effects of early enteral nutrition (EEN), which was initiated within 48 hours, on clinical outcomes in patients with severe acute pancreatitis (SAP). In comparison to delayed enteral nutrition (EN), EEN notably decreased mortality, infectious complications, and organ failure, while also reducing hospitalization duration and enhancing the restoration of gut barrier function. The incidence of feeding intolerance did not rise with the prompt initiation of therapy. These results underscore the importance of timely EN as a secure and efficient therapeutic approach to enhance the prognosis of SAP patients, emphasizing its significance in clinical care.
Citation	Jiang ML, Bao JP, Jiang SC, Xu FG. E Efficacy of early enteral nutrition in patients with severe acute pancreatitis: A prospective cohort study. World J Gastrointest Surg 2026; In press

Received	2025-12-02 09:33
Peer-Review Started	2025-12-02 09:33
First Decision by Editorial Office Director	2025-12-23 05:42
Return for Revision	2025-12-23 05:42
Revised	2026-01-01 13:57
Publication Fee Transferred	2026-01-12 15:30
Second Decision by Editor	2026-01-19 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-19 03:16
Articles in Press	2026-01-19 03:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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