Publication Name	World Journal of Methodology
Manuscript ID	116022
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Do bots provide correct and adequate guidance regarding acidity: A blinded comparison rated by patients and physicians
Manuscript Source	Invited Manuscript
All Author List	Kartikay Goyal, Manjeet Kumar Goyal, Varna Taranikanti, Praneet Wander, Rishi Chowdhary, Shivam Kalra, Gargi Prashar, Ashita Rukmini Vuthaluru and Omesh Goyal
Funding Agency and Grant Number
Corresponding Author	Omesh Goyal, Professor, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. goyalomesh@yahoo.co.in
Key Words	Large language models; Gastroesophageal reflux; Patient education; Empathy; Actionability
Core Tip	This is among the first head-to-head evaluations of ChatGPT-5, Gemini-2.5, and Claude-4 for patient education on acidity (gastroesophageal reflux disease). Physicians rated Gemini-2.5 and Claude-4 highest in accuracy, empathy, and actionability, while patients appreciated ChatGPT-5’s readability. The study underscores trade-offs between clarity and clinical richness and highlights how large language models can complement but not replace clinician-guided patient education.
Citation	Goyal K, Goyal MK, Taranikanti V, Wander P, Chowdhary R, Kalra S, Prashar G, Vuthaluru AR, Goyal O. Do bots provide correct and adequate guidance regarding acidity: A blinded comparison rated by patients and physicians. World J Methodol 2026; In press

Received	2025-11-02 12:32
Peer-Review Started	2025-11-02 12:32
First Decision by Editorial Office Director	2025-12-17 09:29
Return for Revision	2025-12-17 09:29
Revised	2025-12-22 14:47
Publication Fee Transferred
Second Decision by Editor	2026-01-28 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-28 12:37
Articles in Press	2026-01-28 12:37
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
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