Publication Name	World Journal of Gastroenterology
Manuscript ID	116088
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Xpert Ultra and TrueNat MTB plus assays for the diagnosis of gastrointestinal tuberculosis: A diagnostic accuracy study
Manuscript Source	Invited Manuscript
All Author List	Kusum Sharma, Neha Jindal, Megha Sharma, Harshal S Mandavdhare, Pankaj Gupta, Aravind Sekar, Usha Dutta and Vishal Sharma
Funding Agency and Grant Number
Corresponding Author	Vishal Sharma, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh 160012, India. sharma.vishal@pgimer.edu.in
Key Words	Gastrointestinal tuberculosis; Crohn’s disease; Inflammatory bowel disease; Polymerase chain reaction; Intestinal tuberculosis
Core Tip	This study compared Xpert Ultra and TrueNat plus assays for diagnosing gastrointestinal tuberculosis against a composite reference standard. Of 38 patients, 26 had gastrointestinal tuberculosis. Xpert Ultra showed higher sensitivity and specificity than TrueNat plus in intestinal tissue samples. The improved sensitivity of these tests over standard tests comes at a cost of loss of specificity.
Citation	Sharma K, Jindal N, Sharma M, Mandavdhare HS, Gupta P, Sekar A, Dutta U, Sharma V. Xpert Ultra and TrueNat MTB plus assays for the diagnosis of gastrointestinal tuberculosis: A diagnostic accuracy study. World J Gastroenterol 2026; In press

Received	2025-11-02 12:24
Peer-Review Started	2025-11-02 12:24
First Decision by Editorial Office Director	2025-12-17 09:44
Return for Revision	2025-12-17 09:44
Revised	2025-12-30 10:58
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 10:06
Articles in Press	2026-02-02 10:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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