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Articles in Press
1/14/2026 8:28:56 AM | Browse: 1 | Download: 0
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Cancer stem cell markers, chemotherapy response, and survival in triple-negative breast cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Faisal Nabi Depar, Ahmed Jamal Chaudhary, Jawad Hameed, Faisal Sarwar Abbasi, BiBi Uzma, Amjad Ali, Naheed Akhtar, Rizwan Khan, Afsheen Siddiqi and Sohail Riaz |
| Funding Agency and Grant Number |
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| Corresponding Author |
Sohail Riaz, MD, Department of Medicine, International University of Kyrgyzstan, International School of Medicine, 6 Seven April Street, Bishkek 720054, Kyrgyzstan. sohailriaz552@gmail.com |
| Key Words |
Triple-negative breast cancer; Cancer stem cells; CD44; CD24; Aldehyde dehydrogenase 1; Chemotherapy response; Survival; Pakistan |
| Core Tip |
In a Pakistani triple-negative breast cancer cohort, the cancer stem cell phenotype (CD44 high/CD24 low/aldehyde dehydrogenase 1 positive) occurred in 10.2% of cases and independently predicted markedly lower pathological complete response (5.0% vs 51.8%) and shorter overall survival (hazard ratio = 4.35). These findings from a South Asian population with high triple-negative breast cancer burden support cancer stem cell marker integration into risk stratification for personalized therapy in resource-limited settings. |
| Citation |
Depar FN, Chaudhary AJ, Hameed J, Abbasi FS, Uzma B, Ali A, Akhtar N, Khan R, Siddiqi A, Riaz S. Cancer stem cell markers, chemotherapy response, and survival in triple-negative breast cancer World J Clin Oncol 2026; In press |
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Received |
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2025-11-06 14:01 |
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Peer-Review Started |
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2025-11-06 14:01 |
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First Decision by Editorial Office Director |
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2025-12-09 07:21 |
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Return for Revision |
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2025-12-09 08:17 |
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Revised |
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2025-12-11 20:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-14 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-14 08:28 |
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Articles in Press |
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2026-01-14 08:28 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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