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Publication Name World Journal of Gastroenterology
Manuscript ID 116260
Country Sudan
Category Surgery
Manuscript Type Meta-Analysis
Article Title Comparative safety and efficacy of endoscopic band ligation and variceal obturation for gastric varices: Systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Usama Tufail, Eman Khalid, Aleena Ihtasham, Fahad Amin, Muhammad Talha Khan, Fazia Khattak, Taha Alam, Amna Iman, Eeman Afroz, Hina Aslam, Ahtisam Akbar Khan, Tooba Fida and Iman Osman Abufatima
Funding Agency and Grant Number
Corresponding Author Iman Osman Abufatima, Department of Medicine, University of Medical Sciences and Technology, El Riyad area, Square No. 13, Khartoum 11111, Sudan. drimanadam03@gmail.com
Key Words Gastric varices; Portal hypertension; Endoscopic band ligation; Endoscopic variceal obturation; Upper gastrointestinal bleeding; Hemostasis; Rebleeding
Core Tip This meta-analysis of seven randomized controlled trials establishes that while endoscopic variceal ligation (EVL) and endoscopic variceal obturation (EVO) achieve similar initial hemostasis rates for gastric varices, EVO demonstrates superior long-term durability. Specifically, cyanoacrylate injection significantly reduces the risk of rebleeding compared to EVL without increasing overall mortality. These findings support prioritizing cyanoacrylate as the first-line intervention for gastric variceal hemorrhage, reserving EVL as an alternative only when resources for obturation are unavailable.
Citation Tufail U, Khalid E, Ihtasham A, Amin F, Khan MT, Khattak F, Alam T, Iman A, Afroz E, Aslam H, Khan AA, Fida T, Abufatima IO. Comparative safety and efficacy of endoscopic band ligation and variceal obturation for gastric varices: Systematic review and meta-analysis. World J Gastroenterol 2026; In press
Received
2025-11-07 09:14
Peer-Review Started
2025-11-07 09:14
First Decision by Editorial Office Director
2025-12-16 09:53
Return for Revision
2025-12-16 09:53
Revised
2025-12-29 17:49
Publication Fee Transferred
Second Decision by Editor
2026-02-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-25 07:16
Articles in Press
2026-02-25 07:16
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com