Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	116316
Country	Saudi Arabia

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Colonic adenocarcinoma in a pediatric patient: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Marwh G Aldriwesh, Areej Alhareeri, Abdulrahman Alswaji, Maymunah Hakami, Roua Almatrafi, Ayyob Alqarni, Mohammed Alhalafi, Nahar A Alselaim, Mohammed Algarni, Homoud Gh Alawfi, Mohammad Bosaeed, Musaad Altammami and Majed F Alghoribi
Funding Agency and Grant Number	Funding Agency Grant Number King Abdullah International Medical Research Centre, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia No. RC19/181
Corresponding Author	Marwh G Aldriwesh, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, P. O. Box 3660, Riyadh 11481, Saudi Arabia. aldriweshm@ksau-hs.edu.sa
Key Words	Pediatric; Gut microbiota; Genomics; Early onset colorectal cancer; Case report
Core Tip	This case reports a rare diagnosis of colon cancer in a 14-year-old patient, emphasizing the challenges of delayed diagnosis in pediatric patients due to non-specific symptoms and low clinical suspicion. The report uniquely integrates genomic testing and gut microbiota profiling, revealing potential molecular and microbial contributions to pediatric colorectal cancer pathogenesis. These findings underscore the importance of comprehensive evaluation in early-onset cases and suggest a novel direction for research into the role of the gut microbiota in pediatric malignancies, with implications for diagnosis, prognosis, and management strategies.
Citation	Aldriwesh MG, Alhareeri A, Alswaji A, Hakami M, Almatrafi R, Alqarni A, Alhalafi M, Alselaim NA, Algarni M, Alawfi HG, Bosaeed M, Altammami M, Alghoribi MF. Colonic adenocarcinoma in a pediatric patient: A case report and review of literature. World J Gastrointest Oncol 2026; In press

Received	2025-11-10 15:46
Peer-Review Started	2025-11-11 03:46
First Decision by Editorial Office Director	2025-12-02 10:14
Return for Revision	2025-12-04 09:14
Revised	2025-12-28 16:53
Publication Fee Transferred	2026-01-01 10:23
Second Decision by Editor	2026-02-02 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 09:25
Articles in Press	2026-02-02 09:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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