Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	116412
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Navigation value of intraoperative ultrasound combined with indocyanine green fluorescence in complex hepatocellular carcinoma resection
Manuscript Source	Unsolicited Manuscript
All Author List	Sheng Zhang, Shao-Ying Li and Bing Zhou
Funding Agency and Grant Number
Corresponding Author	Bing Zhou, Associate Chief Physician, Department of Hepatobiliary, Pancreatic and Splenic Surgery, The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui 453100, Henan Province, China. zhoubing202511@163.com
Key Words	Hepatocellular carcinoma; Complex hepatocellular carcinoma; Intraoperative ultrasound; Indocyanine green fluorescence imaging; Surgical navigation; Precision hepatectomy
Core Tip	This retrospective study evaluated 200 patients with complex hepatocellular carcinoma undergoing radical hepatectomy. Intraoperative ultrasound combined with indocyanine green fluorescence imaging significantly improved tumor localization, increased R0 resection and anatomical hepatectomy rates, reduced intraoperative blood loss and postoperative complications, and enhanced long-term survival compared with conventional surgery. The combined navigation approach provides real-time visualization and precise resection guidance, offering a safe, effective, and clinically valuable strategy for precision hepatectomy in complex hepatocellular carcinoma.
Citation	Zhang S, Li SY, Zhou B. Navigation value of intraoperative ultrasound combined with indocyanine green fluorescence in complex hepatocellular carcinoma resection. World J Gastrointest Surg 2026; In press

Received	2025-11-25 09:11
Peer-Review Started	2025-11-25 09:11
First Decision by Editorial Office Director	2025-12-30 05:43
Return for Revision	2025-12-30 05:43
Revised	2026-01-14 14:23
Publication Fee Transferred	2026-01-16 06:08
Second Decision by Editor	2026-02-12 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-12 04:05
Articles in Press	2026-02-12 04:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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