Publication Name	World Journal of Diabetes
Manuscript ID	116538
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Letter to the Editor
Article Title	Bridging oncology and metabolism: Personalized exercise improves glycemic and nutritional outcomes in diabetic colorectal cancer patients under chemotherapy
Manuscript Source	Invited Manuscript
All Author List	Zhi-Chao Zheng and Chao-Ban Wang
Funding Agency and Grant Number
Corresponding Author	Chao-Ban Wang, Department of Pediatrics, West China Second University Hospital, Sichuan University, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China., Chengdu 610000, Sichuan Province, China. chaobanwang@scu.edu.cn
Key Words	Individualized exercise training; Type 2 diabetes mellitus; Colorectal cancer; Chemotherapy; Oncometabolic management
Core Tip	This letter highlights the innovative integration of individualized exercise training (IET)—combining aerobic and resistance modalities—to simultaneously improve glycemic control and nutritional status in patients with type 2 diabetes mellitus undergoing chemotherapy for colorectal cancer. By targeting both insulin resistance and sarcopenia, IET emerges as a feasible, non-pharmacological strategy to enhance treatment tolerance and metabolic outcomes in this high-risk comorbid population, reinforcing the concept of “exercise as medicine” in oncometabolic care.
Citation	Zheng ZC, Wang CB. Bridging oncology and metabolism: Personalized exercise improves glycemic and nutritional outcomes in diabetic colorectal cancer patients under chemotherapy. World J Diabetes 2025; In press

Received	2025-11-14 04:56
Peer-Review Started	2025-11-14 06:36
First Decision by Editorial Office Director	2025-11-28 07:53
Return for Revision	2025-11-28 07:53
Revised	2025-12-05 01:29
Publication Fee Transferred
Second Decision by Editor	2025-12-18 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-18 06:31
Articles in Press	2025-12-18 06:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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