Publication Name	World Journal of Hepatology
Manuscript ID	116562
Country	Iraq

Category	Medicine, Research & Experimental
Manuscript Type	Letter to the Editor
Article Title	Improving the reliability of functional capacity testing in liver cirrhosis: A novel assessment direction
Manuscript Source	Invited Manuscript
All Author List	Marwan SM Al-Nimer
Funding Agency and Grant Number
Corresponding Author	Marwan SM Al-Nimer, Clinical Pharmacology and Therapeutics, College of Medicine, University of Diyala, University Street, Bagubah 32001, Diyala, Iraq. alnimermarwan@ymail.com
Key Words	Liver cirrhosis; 6-minute walking test; Myokines
Core Tip	The six-minute walking test (6MWT) is useful in the assessment of functional capacity in a wide variety of diseases, including liver cirrhosis (LC). The development of sarcopenia is one cause of the deterioration of functional capacity in LC, and it is linked to a decline in the regulators of muscle growth. Therefore, the determination of the exerkine (myokine) levels, e.g., irisin, myostatin, and follistatin, as a supplement to the 6MWT, is of value in supporting the assessment of the functional capacity in LC.
Citation	Al-Nimer MS. Improving the reliability of functional capacity testing in liver cirrhosis: A novel assessment direction. World J Hepatol 2026; In press

Received	2025-11-14 04:36
Peer-Review Started	2025-11-14 04:36
First Decision by Editorial Office Director	2025-12-24 10:13
Return for Revision	2025-12-24 10:13
Revised	2026-01-08 18:23
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 12:46
Articles in Press	2026-02-02 12:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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