Publication Name	World Journal of Nephrology
Manuscript ID	116620
Country	Brazil

Category	Medicine, General & Internal
Manuscript Type	Case Report
Article Title	Five-year follow-up sustained remission with rituximab in a patient with focal segmental glomerulosclerosis: A case report
Manuscript Source	Invited Manuscript
All Author List	Ana Flávia Moura, Paulo Novis Rocha, Daniela Moura-Landim, Jose A Moura Jr and José A Moura-Neto
Funding Agency and Grant Number
Corresponding Author	Ana Flávia Moura, Department of Medicine, Bahiana School of Medicine and Public Health, Av D. Joao VI, Salvador 40290-000, Bahia, Brazil. anaflaviapsouza@gmail.com
Key Words	Glomerulonephritis; Glomeruloesclerosis; Focal segmental glomerulosclerosis; Proteinuria; Rituximab; Case report
Core Tip	This case report describes a patient with steroid- and calcineurin inhibitor-dependent primary focal segmental glomerulosclerosis (FSGS) who achieved complete and sustained remission for five years following a two-dose regimen of rituximab (RTX). The case highlights the potential of RTX as a steroid- and calcineurin inhibitor-sparing agent in adult FSGS, particularly in patients with significant toxicity or dependence on standard immunosuppressive therapy. The extended follow-up adds valuable insight into the long-term efficacy and safety of RTX in this challenging population.
Citation	Moura AF, Rocha PN, Moura-Landim D, Moura Jr JA, Moura-Neto JA. Five-year follow-up sustained remission with rituximab in a patient with focal segmental glomerulosclerosis: A case report. World J Nephrol 2025; In press

Received	2025-11-17 04:41
Peer-Review Started	2025-11-17 07:25
First Decision by Editorial Office Director	2025-11-19 10:15
Return for Revision	2025-11-19 10:15
Revised	2025-12-01 13:56
Publication Fee Transferred
Second Decision by Editor	2025-12-23 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-23 04:02
Articles in Press	2025-12-23 04:02
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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