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Articles in Press
5/6/2026 9:32:14 AM | Browse: 14 | Download: 0
| Category |
Neurosciences |
| Manuscript Type |
Case Report |
| Article Title |
Novel PSEN1 (Q223 L) mutation causes early-onset Alzheimer’s disease: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jie Li, Fen-Li Zhou, Juan-Juan Chen, Zhi-Jian Lin, Xin Shi, Guo-Gao Zhang, Hong-Jie Yang, Meng-Jie Dong, Li Yi, Jun Hu and Xu-Hui Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shenzhen Basic Research Program |
No. JCYJ20241202124859016 |
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| Corresponding Author |
Xu-Hui Chen, MD, PhD, Department of Neurology, Peking University Shenzhen Hospital, Lianhua Road, Shenzhen 518000, Guangdong Province, China. xuhuichen@pkuszh.com |
| Key Words |
Alzheimer’s disease; Mutation; PSEN1; Gene; Pathogenic; Case report |
| Core Tip |
We identified a novel p.Gln223 Leu mutation in PSEN1 in a patient with early-onset Alzheimer’s disease, thus providing a valuable contribution to the genetic diagnosis and understanding of the pathogenesis of Alzheimer’s disease. |
| Citation |
Li J, Zhou FL, Chen JJ, Lin ZJ, Shi X, Zhang GG, Yang HJ, Dong MJ, Yi L, Hu J, Chen XH. Novel PSEN1 (Q223 L) mutation causes early-onset Alzheimer’s disease: A case report. World J Radiol 2026; In press |
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Received |
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2025-11-17 04:56 |
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Peer-Review Started |
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2025-11-17 04:56 |
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First Decision by Editorial Office Director |
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2025-12-03 10:11 |
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Return for Revision |
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2025-12-03 10:12 |
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Revised |
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2025-12-31 11:04 |
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Publication Fee Transferred |
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2026-01-26 14:50 |
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Second Decision by Editor |
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2026-05-06 03:18 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-06 09:32 |
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Articles in Press |
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2026-05-06 09:32 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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