Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	116672
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Prognostic value of serum aldo-keto reductase family 1 member B10 in hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Yun-Ling Du, Chang-Jiang Shi, Fang-Yuan Gao, Shou-Jun Xie, Meng-Na Zhang, Zhu-Qing Zhang, Wei Qiu and Ying Ming
Funding Agency and Grant Number	Funding Agency Grant Number the Science and Technology Program of Chengde 202109A064
Corresponding Author	Ying Ming, Department of Laboratory Medicine, The Affiliated Hospital of Chengde Medical University, No. 36 Nanyingzi Street, Shuangqiao District, Chengde 067000, Hebei Province, China. 18503145756@163.com
Key Words	Hepatocellular carcinoma; Aldo-keto reductase family 1 member B10; Prognosis; Serum biomarker; Molecular biomarkers
Core Tip	Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. Despite recent improvements in diagnostic approaches and surgical techniques, the five-year survival rate for patients with advanced HCC remains low, largely due to the absence of early clinical symptoms and the lack of reliable diagnostic and prognostic biomarkers. Over the past decade, aldo–keto reductase family 1 member 10 (AKR1B10) has emerged as a potential biomarker for both the diagnosis and prognosis of HCC. This study aimed to investigate the correlation between serum AKR1B10 Levels and prognosis in patients with HCC, evaluate its clinical value as a prognostic indicator, and provide a theoretical basis and research direction for individualized treatment strategies.
Citation	Du YL, Shi CJ, Gao FY, Xie SJ, Zhang MN, Zhang ZQ, Qiu W, Ming Y. Prognostic value of serum aldo-keto reductase family 1 member B10 in hepatocellular carcinoma. World J Gastrointest Surg 2026; In press

Received	2026-01-13 10:34
Peer-Review Started	2026-01-13 10:34
First Decision by Editorial Office Director	2026-01-20 06:07
Return for Revision	2026-01-20 06:07
Revised	2026-02-04 14:27
Publication Fee Transferred	2026-02-11 02:58
Second Decision by Editor	2026-03-10 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-10 07:07
Articles in Press	2026-03-10 07:07
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Typeset the Manuscript

ISSN	1948-9366 (online)
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