Publication Name	World Journal of Orthopedics
Manuscript ID	116723
Country	India

Category	Orthopedics
Manuscript Type	Systematic Reviews
Article Title	Systematic review and meta-analysis on vitamin C in musculoskeletal disorders
Manuscript Source	Invited Manuscript
All Author List	Madhan Jeyaraman, Naveen Jeyaraman, Mainak Roy, Arulkumar Nallakumarasamy, Abdus Sami, Sathish Muthu, Karthikeyan P Iyengar and Vijay Kumar Jain
Funding Agency and Grant Number
Corresponding Author	Madhan Jeyaraman, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nādu, India. madhanjeyaraman@gmail.com
Key Words	Vitamin C; Musculoskeletal disorders; Analgesia; Inflammation; Tissue repair; Antioxidants
Core Tip	Vitamin C emerges as a promising adjunct therapy for musculoskeletal disorders, offering significant benefits in pain reduction, functional improvement, and tissue regeneration. Evidence pooled from 30 studies underscores its role in enhancing collagen synthesis and mitigating inflammation. These findings support the integration of vitamin C into musculoskeletal disorder management strategies and highlight the need for further high-quality trials to refine dosage recommendations and confirm its therapeutic value in orthopedic care.
Citation	Jeyaraman M, Jeyaraman N, Roy M, Nallakumarasamy A, Sami A, Muthu S, Iyengar KP, Jain VK. Systematic review and meta-analysis on vitamin C in musculoskeletal disorders. World J Orthop 2026; In press

Received	2025-11-19 07:08
Peer-Review Started	2025-11-19 09:29
First Decision by Editorial Office Director	2025-12-17 09:00
Return for Revision	2025-12-17 09:00
Revised	2025-12-22 19:40
Publication Fee Transferred
Second Decision by Editor	2026-02-06 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-06 09:42
Articles in Press	2026-02-06 09:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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