Publication Name	World Journal of Cardiology
Manuscript ID	116789
Country	Sudan

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Nicorandil in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Shahzaib Ahmed, Eeman Ahmad, Hamza Ashraf, Hoor Ul Ain, Shoaib Ahmad, Umar Akram, Jawad Basit, Ibrahim Nagmeldin Hassan, Irfan Ullah, Raheel Ahmed, Gregg C Fonarow and Bernardo Cortese
Funding Agency and Grant Number
Corresponding Author	Ibrahim Nagmeldin Hassan, Department of Medicine, University of Khartoum, Faculty of Medicine, ElQasr Avenue, Khartoum 11111, Sudan. ibrahimnagmmrcp@gmail.com
Key Words	Nicorandil; Percutaneous coronary intervention; ST-segment elevation myocardial infarction; Myocardial perfusion; Myocardial infarction
Core Tip	Nicorandil, a nitrate-like agent that opens adenosine triphosphate-sensitive potassium channels, has been studied as an adjunct during primary percutaneous coronary intervention for ST-elevation myocardial infarction. In this systematic review and meta-analysis of randomized trials, nicorandil improved ST-segment resolution, Thrombolysis in Myocardial Infarction grade 3 flow, and Thrombolysis in Myocardial Perfusion grade 3. It also enhanced left ventricular function and lowered major adverse cardiovascular events. These findings support its value in reducing microvascular injury and improving post-percutaneous coronary intervention outcomes.
Citation	Ahmed S, Ahmad E, Ashraf H, Ain HU, Ahmad S, Akram U, Basit J, Hassan IN, Ullah I, Ahmed R, Fonarow GC, Cortese B. Nicorandil in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis. World J Cardiol 2026; In press

Received	2025-11-20 08:01
Peer-Review Started	2025-11-20 08:01
First Decision by Editorial Office Director	2025-11-30 01:21
Return for Revision	2025-11-30 01:21
Revised	2025-12-13 15:22
Publication Fee Transferred
Second Decision by Editor	2026-02-12 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-12 08:53
Articles in Press	2026-02-12 08:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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