Publication Name	World Journal of Gastroenterology
Manuscript ID	116857
Country	United Arab Emirates

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Inflammatory markers as bridges to the mind in postoperative intestinal tumor recovery
Manuscript Source	Invited Manuscript
All Author List	Iyad A Issa and Taly Issa
Funding Agency and Grant Number
Corresponding Author	Iyad A Issa, Department of Gastroenterology and Hepatology, Harley Street Medical Center, Marina Village, Villa No. A21, Abu Dhabi 41475, United Arab Emirates. iyadissa71@gmail.com
Key Words	Postoperative depression; Intestinal tumor surgery; Inflammatory markers; Neutrophil-to-lymphocyte ratio; Albumin-to-fibrinogen ratio; Quality of life; Precision oncology; Integrated care
Core Tip	Wei et al transform routine inflammatory markers into psychological risk stratification tools by demonstrating that neutrophil-to-lymphocyte ratio > 7.0 and albumin-to-fibrinogen ratio < 12.0 mechanistically predict postoperative depression and anxiety in intestinal tumor patients. This paradigm shift enables early identification of vulnerable patients using existing clinical infrastructure, facilitating integrated physical-mental rehabilitation that addresses the biological roots of postoperative psychological distress rather than treating mind and body as separate domains.
Citation	Issa IA, Issa T. Inflammatory markers as bridges to the mind in postoperative intestinal tumor recovery. World J Gastroenterol 2026; In press

Received	2025-11-24 04:05
Peer-Review Started	2025-11-24 04:06
First Decision by Editorial Office Director	2025-12-16 09:56
Return for Revision	2025-12-16 09:56
Revised	2025-12-18 13:55
Publication Fee Transferred
Second Decision by Editor	2026-02-03 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-03 05:37
Articles in Press	2026-02-03 05:37
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com