Publication Name	World Journal of Orthopedics
Manuscript ID	116878
Country	United States

Category	Orthopedics
Manuscript Type	Editorial
Article Title	Does the application of intrawound and prolonged systemic antibiotics decrease spine postoperative surgical site infection?
Manuscript Source	Invited Manuscript
All Author List	Hossein Elgafy, Rachel Michael, Christopher Jackson and Connor Burke
Funding Agency and Grant Number
Corresponding Author	Hossein Elgafy, Departments of Orthopedic, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH 43614-5807, United States. hossein.elgafy@utoledo.edu
Key Words	Antibiotic; Prolonged; Vancomycin; Spine; Postoperative infection
Core Tip	Postoperative spine surgery wound infection has been reported up to 10.9%. Several factors have been identified as risk factors for surgical site infection. Staphylococcus aureus is the most commonly isolated bacterium. A new biomarker, presepsin, has been recently investigated as a possible indicator of infection, and an elevated level (> 300 pg/mL) could be used as a sign of surgical site infection. Using local as well as prolonged postoperative systemic antibiotics is recommended in certain groups of patients who have a higher risk of surgical site infection.
Citation	Elgafy H, Michael R, Jackson C, Burke C. Does application of intrawound and prolonged systemic antibiotics decrease spine postoperative surgical site infection? World J Orthop 2026; In press

Received	2025-11-24 01:51
Peer-Review Started	2025-11-24 05:40
First Decision by Editorial Office Director	2025-11-30 01:30
Return for Revision	2025-11-30 01:30
Revised	2025-12-11 04:19
Publication Fee Transferred
Second Decision by Editor	2026-01-15 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-15 09:44
Articles in Press	2026-01-15 09:44
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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