Publication Name	World Journal of Stem Cells
Manuscript ID	117067
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Observational Study
Article Title	Association of peripheral blood-derived mesenchymal stem cells exosomal circular RNAs with diagnosis and inflammatory response in acute mesenteric ischemia
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Liang Wang, Qing Li, Jian-Qi Ni, Yi-Feng Shen, Liu Xu and Qin Jin
Funding Agency and Grant Number	Funding Agency Grant Number Joint Development of Disciplines by Jiaxing City and Provincial Government National Key Clinical Specialty Construction Project 2023-GJZK-001
Corresponding Author	Qin Jin, Chief Physician, Department of Vascular Surgery, First Hospital of Jiaxing, Affiliated Hospital of Jiaxing University, No. 1882 Zhonghuan South Road, Jiaxing 314001, Zhejiang Province, China. chinekim@163.com
Key Words	Peripheral blood-derived mesenchymal stem cells; Exosome; Circular RNAs; Acute mesenteric ischemia; Diagnosis; Inflammatory factors
Core Tip	Peripheral blood-derived mesenchymal stem cells exosomal circ-Eya3 and circEZH2_005 serve as novel biomarkers for acute mesenteric ischemia (AMI), reflecting intestinal injury severity, systemic inflammation, and disease subtype. Their integration with D-lactate enables high-accuracy diagnosis, whereas differential expression across arterial/venous AMI and ischemia stages offers clinical utility for guiding intervention strategies. Peripheral blood-derived mesenchymal stem cells exosomal circ-Eya3 and circEZH2_005 are promising biomarkers for the early diagnosis, subtyping, staging, and post-reperfusion monitoring of AMI.
Citation	Wang GL, Li Q, Ni JQ, Shen YF, Xu L, Jin Q. Association of peripheral blood-derived mesenchymal stem cells exosomal circular RNAs with diagnosis and inflammatory response in acute mesenteric ischemia. World J Stem Cells 2026; In press

Received	2025-12-05 08:41
Peer-Review Started	2025-12-05 08:41
First Decision by Editorial Office Director	2025-12-30 05:44
Return for Revision	2025-12-30 05:44
Revised	2026-01-04 02:28
Publication Fee Transferred	2026-01-06 05:36
Second Decision by Editor	2026-02-02 03:04
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-09 09:06
Articles in Press	2026-02-09 09:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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