Publication Name	World Journal of Cardiology
Manuscript ID	117111
Country	Spain

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Letter to the Editor
Article Title	Takotsubo syndrome and neurological disorders within the neurocardiology framework
Manuscript Source	Unsolicited Manuscript
All Author List	Jorge Salamanca
Funding Agency and Grant Number
Corresponding Author	Jorge Salamanca, MD, Senior Researcher, Department of Cardiology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Universidad Autónoma de Madrid, Madrid 28002, Spain. jsalamancaviloria@gmail.com
Key Words	Neurocardiology; Takotsubo syndrome; Neurological disorders; Brain-heart axis; Autonomic nervous system
Core Tip	Takotsubo syndrome epitomizes neurocardiology: Acute sympathetic surges, central autonomic imbalance, and inflammatory activation converge to produce reversible myocardial dysfunction. Evidence from a large international takotsubo registry shows that neurological disorders identify a high-risk subgroup with increased early and late mortality. Integrating takotsubo syndrome into the emerging neurocardiology framework may enhance risk stratification, early recognition of vulnerable phenotypes, and coordinated care between neurologists and cardiologists.
Citation	Salamanca J. Takotsubo syndrome and neurological disorders within the neurocardiology framework. World J Cardiol 2026; In press

Received	2025-11-28 01:08
Peer-Review Started	2025-11-28 01:08
First Decision by Editorial Office Director	2025-12-26 10:26
Return for Revision	2025-12-26 10:26
Revised	2026-01-03 16:03
Publication Fee Transferred
Second Decision by Editor	2026-02-13 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-13 06:10
Articles in Press	2026-02-13 06:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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