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Publication Name World Journal of Clinical Oncology
Manuscript ID 117161
Country China
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Deep margin positivity in small rectal neuroendocrine tumors: Pathological insights for post-endoscopic submucosal dissection management
Manuscript Source Invited Manuscript
All Author List Ling-Feng Zou, Yan Luo and Cheng-Long Wang
Funding Agency and Grant Number
Funding Agency Grant Number
the Chongqing Health Commission and Science and Technology Bureau 2023MSXM060
Corresponding Author Cheng-Long Wang, MD, PhD, Department of Pathology, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi 7 branch Road, Jiangbei District, Chongqing 400021, China. qq171909771@gmail.com
Key Words Rectal neuroendocrine tumor; Endoscopic submucosal dissection; Positive vertical margin; Non-R0 resection; Pathologic margin assessment
Core Tip Positive vertical margins after endoscopic resection of small, well-differentiated rectal neuroendocrine tumors do not necessarily indicate residual disease. Technical artifacts and the intrinsic indolence of G1 tumors support a risk-adapted, surveillance-based approach rather than routine salvage surgery after non-R0 resection.
Citation Zou LF, Luo Y, Wang CL. Deep margin positivity in small rectal neuroendocrine tumors: Pathological insights for post-endoscopic submucosal dissection management. World J Clin Oncol 2026; In press
Received
2025-12-01 01:43
Peer-Review Started
2025-12-01 01:43
First Decision by Editorial Office Director
2026-01-08 07:36
Return for Revision
2026-01-08 07:36
Revised
2026-01-20 14:29
Publication Fee Transferred
Second Decision by Editor
2026-02-13 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-13 06:26
Articles in Press
2026-02-13 06:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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