Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	117170
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Preoperative-pathologic discordance as a structural weakness in early gastric cancer management
Manuscript Source	Invited Manuscript
All Author List	Hai-Fu Huang and Jing-Qi Zeng
Funding Agency and Grant Number	Funding Agency Grant Number the Special Fund for Basic Research of Shenzhen City (2025) - Natural Science Foundation Program Project JCYJ20250604190104007 2025 Scientific Research Project of the Health System in Futian District, Shenzhen FTWS2025107
Corresponding Author	Jing-Qi Zeng, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Yangguang South Street, Liangxiang Higher Education Park Fangshan District, Beijing 102488, China. zjingqi@163.com
Key Words	Early gastric cancer; Endoscopic submucosal dissection; Preoperative-pathologic discordance; Diagnostic accuracy; Artificial intelligence; Treatment algorithms
Core Tip	Preoperative-pathologic discordance is a common and clinically important issue in early gastric cancer management. Clinicians should recognize high-risk features early and escalate diagnostic evaluation when appropriate to preserve organ-sparing treatment options. The use of enhanced diagnostic techniques, such as targeted biopsies, virtual chromoendoscopy, and endoscopic ultrasonography, can significantly improve staging accuracy and help guide better treatment decisions, ultimately reducing unnecessary surgeries.
Citation	Huang HF, Zeng JQ. Preoperative-pathologic discordance as a structural weakness in early gastric cancer management. World J Gastrointest Oncol 2026; In press

Received	2025-12-01 03:16
Peer-Review Started	2025-12-01 03:16
First Decision by Editorial Office Director	2026-01-09 07:50
Return for Revision	2026-01-09 07:50
Revised	2026-01-10 13:49
Publication Fee Transferred
Second Decision by Editor	2026-01-19 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-19 04:38
Articles in Press	2026-01-19 04:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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