Publication Name	World Journal of Psychiatry
Manuscript ID	117216
Country	China

Category	Psychology
Manuscript Type	Retrospective Study
Article Title	Effects of phototherapy plus agomelatine on efficacy, negative emotions, and neurotransmitter levels in elderly patients with depressive disorders
Manuscript Source	Unsolicited Manuscript
All Author List	Ping-Jing Jiang, Shu-Wei Hu, Chun-Mei Liao, Jing-Jing Peng, Sheng-Jian Liang and Xue Cheng
Funding Agency and Grant Number
Corresponding Author	Xue Cheng, Associate Chief Physician, Department of Psychiatry, Chongqing Mental Health Center, No. 102 Jinzi Mountain, Chongqing 401147, China. chengxue000331@126.com
Key Words	Phototherapy; Agomelatine; Senile depressive disorder; Treatment efficacy; Negative emotions; Neurotransmitter
Core Tip	Drug therapy, psychotherapy, and combined drug-psychological therapy are available treatment options for elderly patients with depressive disorders; however, therapeutic efficacy remains suboptimal. This study evaluated phototherapy combined with agomelatine in elderly patients with depressive disorders. The findings indicate that the combined therapy demonstrated significant treatment efficacy, effectively alleviated anxiety and depression, improved sleep quality, regulated neurotransmitter levels, and suppressed oxidative stress, without increasing adverse side effects.
Citation	Jiang PJ, Hu SW, Liao CM, Peng JJ, Liang SJ, Cheng X. Effects of phototherapy plus agomelatine on efficacy, negative emotions, and neurotransmitter levels in elderly patients with depressive disorders. World J Psychiatry 2026; In press

Received	2026-01-23 09:55
Peer-Review Started	2026-01-23 09:55
First Decision by Editorial Office Director	2026-02-06 08:58
Return for Revision	2026-02-06 08:58
Revised	2026-03-02 03:32
Publication Fee Transferred	2026-03-07 05:39
Second Decision by Editor	2026-04-08 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-08 04:36
Articles in Press	2026-04-08 04:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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