Publication Name	World Journal of Gastroenterology
Manuscript ID	117259
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Monomorphic epitheliotropic intestinal T-cell lymphoma: Clinical, endoscopic and pathological features
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Juan Jiang, Cheng-Zhu Ou, Hao Tang, Mu-Han Li, Cong-Wei Jia, Wei-Xun Zhou, Zhang-Yu-Ting He, Ji Li, Yan Zhang and Jing-Nan Li
Funding Agency and Grant Number	Funding Agency Grant Number Chinese Academy of Medical Sciences Innovations Fund for Medical Sciences 2021-I2M-1-003 Beijing Research Ward Excellence Program BRWEP2024W034010110
Corresponding Author	Ji Li, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, No. 1 Shuaifuyuan, Wangfujing, Beijing 100730, China. liji0235@pumch.cn
Key Words	Monomorphic epitheliotropic intestinal T-cell lymphoma; Endoscopic features; Clinical characteristics; Pathological characteristics; Diagnosis
Core Tip	This study analyzed 26 cases from Peking Union Medical College Hospital and 130 literature-reported cases of monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL). It found heterogeneous endoscopic manifestations. The Peking Union Medical College Hospital cohort mainly presented with subtle mucosal changes (edema, roughness, villous blunting), which may be early endoscopic signs of MEITL. Ulceration was the main endoscopic feature in the literature cohort, likely indicating disease progression. Multi-site deep biopsy combined with imaging is crucial for early accurate diagnosis of MEITL. Two clinical subtypes (acute aggressive and chronic consumptive) were identified, with distinct symptoms and pathological features, providing value for personalized clinical management.
Citation	Jiang SJ, Ou CZ, Tang H, Li MH, Jia CW, Zhou WX, He ZYT, Li J, Zhang Y, Li JN. Monomorphic epitheliotropic intestinal T-cell lymphoma: Clinical, endoscopic and pathological features. World J Gastroenterol 2026; In press

Received	2025-12-03 02:07
Peer-Review Started	2025-12-03 02:07
First Decision by Editorial Office Director	2025-12-17 10:21
Return for Revision	2025-12-17 10:21
Revised	2025-12-23 06:33
Publication Fee Transferred	2026-01-04 13:40
Second Decision by Editor	2026-01-29 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-29 07:06
Articles in Press	2026-01-29 07:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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