Publication Name	World Journal of Gastroenterology
Manuscript ID	117264
Country	Ireland

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Enteroscopy and ablation of small bowel angiodysplasia improves quality-of-life and fatigue: A prospective study including biomarker assessment
Manuscript Source	Unsolicited Manuscript
All Author List	Thomas Butler, Fintan O’Hara, Conor Costigan, Sandeep Sihag, Divya Kripakaran and Deirdre McNamara
Funding Agency and Grant Number
Corresponding Author	Deirdre McNamara, Professor, TAGG Research Centre, Clinical Medicine, Tallaght University Hospital, Belgard Square North, Dublin D24 NR0A, Ireland. mcnamad@tcd.ie
Key Words	Small bowel angiodysplasia; Balloon assisted enteroscopy; Quality of life; Angiogenic factors; Fatigue
Core Tip	This prospective study in subjects with small bowel angiodysplasia has demonstrated that endoscopic intervention with balloon assisted enteroscopy and argon plasma coagulation has a positive impact on both patient reported quality of life and fatigue severity. The beneficial affect is independent of age, gender and baseline haemoglobin levels. The study supports the use of balloon assisted enteroscopy and argon plasma coagulation as a cornerstone of small bowel angiodysplasia treatment, particularly for those with multiple lesions and those amenable to intervention, as benefit was demonstrated without adjunctive medical therapy. Endostatin would appear to be a potential biomarker for response and warrants additional investigation.
Citation	Butler T, O’Hara F, Costigan C, Sihag S, Kripakaran D, McNamara D. Enteroscopy and ablation of small bowel angiodysplasia improves quality-of-life and fatigue: A prospective study including biomarker assessment. World J Gastroenterol 2026; In press

Received	2025-12-03 02:18
Peer-Review Started	2025-12-03 02:18
First Decision by Editorial Office Director	2026-01-07 09:24
Return for Revision	2026-01-07 09:24
Revised	2026-01-13 10:01
Publication Fee Transferred	2026-01-17 16:09
Second Decision by Editor	2026-02-13 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-13 08:04
Articles in Press	2026-02-13 08:04
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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