Publication Name	World Journal of Clinical Oncology
Manuscript ID	117391
Country	China

Category	Multidisciplinary Sciences
Manuscript Type	Editorial
Article Title	Immune checkpoint co-expression combined with systemic inflammatory index: A promising approach in prognostic evaluation of lymphoma in Egypt
Manuscript Source	Invited Manuscript
All Author List	Zu-Chian Chiang, Ji-Zhen Lin and Qi Chen
Funding Agency and Grant Number
Corresponding Author	Qi Chen, Professor, Biomedical Research Center of South China, Fujian Key Laboratory of Innate Immune Biology, Biomedical Research Center of South China, College of Life Science, Fujian Normal University, No. 8 Shangsan Road, Cangshan District, Fuzhou 350117, Fujian Province, China. chenqi@fjnu.edu.cn
Key Words	Lymphoproliferative neoplasms; Immune checkpoint; Co-expression; Systemic inflammatory response index; Prognostic biomarker; Hepatitis C virus; Resource-limited settings; Therapeutic monitoring
Core Tip	This editorial highlights a novel prognostic model that combines immune checkpoint co-expression and the systemic inflammatory response index. Notably, programmed death-ligand 1/C-X-C motif chemokine receptor 3 co-expression accurately identifies stage IV lymphoma, while systemic inflammatory response index effectively distinguishes advanced disease and decreases with effective treatment. This low-cost biomarker system improves patient stratification, supports treatment monitoring, and promotes healthcare equity in resource-constrained settings.
Citation	Chiang ZC, Lin JZ, Chen Q. Immune checkpoint co-expression combined with systemic inflammatory index: A promising approach in prognostic evaluation of lymphoma in Egypt. World J Clin Oncol 2026; In press

Received	2025-12-08 00:53
Peer-Review Started	2025-12-08 00:53
First Decision by Editorial Office Director	2026-01-20 09:14
Return for Revision	2026-01-20 09:14
Revised	2026-02-02 02:03
Publication Fee Transferred
Second Decision by Editor	2026-03-10 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-10 10:54
Articles in Press	2026-03-10 10:54
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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