| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Proposal of a new classification scheme for complete portal vein thrombosis and its clinical significance: A retrospective study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Fan Lv, Bo-Wen Liu, Ying Han, Ming-Ming Meng, Dong-Ze Li, Hua Tian, Fu-Chuan Wang, Jing-Hui Dong, Yong-Ping Yang, Guang-De Zhou, Hui-Guo Ding, Yue-Ning Zhang, Fu-Quan Liu and Bing Zhu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project |
No. 2025ZD01906302 |
| Talent Training Plan During the “14th Five-Year Plan” of Beijing Shijitan Hospital Affiliated with Capital Medical University |
No. 2023 LJRCLFQ |
|
| Corresponding Author |
Bing Zhu, Department of Liver Diseases, The Fifth Medical Center of Chinese People’s Liberation Army General Hospital, No. 100 West Fourth Ring Middle Road, Fengtai District, Beijing 100039, China. zhubing302@163.com |
| Key Words |
Complete portal vein thrombosis; Medical imaging; Thrombus composition; Thrombus pathology; Computed tomography |
| Core Tip |
This study aimed to analyze contrast-enhanced computed tomography imaging features of complete portal vein thrombosis and establish a novel imaging-based classification system with clinical relevance. In a retrospective multicenter analysis of 171 patients, thrombus samples from 102 cases were examined pathologically. Four distinct thrombus types were identified: Acute (26.9%), chronic (34.5%), cavernous transformation (12.9%), and mixed (25.7%), each characterized by specific radiological and pathological profiles. Treatment resulted in a significant reduction in portal pressure gradient across all groups (P < 0.001), supporting the clinical utility of the proposed classification in guiding therapeutic strategy. |
| Citation |
Lv YF, Liu BW, Han Y, Meng MM, Li DZ, Tian H, Wang FC, Dong JH, Yang YP, Zhou GD, Ding HG, Zhang YN, Liu FQ, Zhu B. Proposal of a new classification scheme for complete portal vein thrombosis and its clinical significance: A retrospective study. World J Gastroenterol 2026; In press |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
