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Articles in Press
6/15/2026 7:00:58 AM | Browse: 4 | Download: 0
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
Dynamic regulation of neural stem cell state transitions by NOTCH1-REST transcriptional axis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Chong Xie, Xiao-Yong Zhao, Rui-Hua Xiong, Xiao-Li Zhang and Wei Yang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangzhou Municipal Science and Technology Bureau University Project |
2025A03J3232 |
| Guangdong Provincial Graduate Education Innovation Project |
2024JGXM_158 |
| Futian District Health and Wellness Project of Shenzhen |
FTWS059 |
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| Corresponding Author |
Wei Yang, Department of Physical Examination, Guangzhou Xinhai Hospital, No. 167 Xingang West Road, Haizhu District, Guangzhou 510275, Guangdong Province, China. yuki20152025@163.com |
| Key Words |
Neural stem cells; Neurogenic locus notch homolog protein 1-RE1-silencing transcription factor axis; Epigenetic; Organoid model; Neural repair |
| Core Tip |
This study unveils the neurogenic locus notch homolog protein 1-RE1-silencing transcription factor axis as a pivotal molecular switch controlling neural stem cell dormancy-activation transitions. By integrating transcriptional, epigenetic, and metabolic analyses, it elucidates the dynamic regulatory interplay of neurogenic locus notch homolog protein 1 and RE1-silencing transcription factor, offering crucial insights into neural stem cell state transitions. The findings present promising targets for central nervous system injury repair and regenerative therapies for neurodegenerative diseases. |
| Citation |
Xie ZC, Zhao XY, Xiong RH, Zhang XL, Yang W. Dynamic regulation of neural stem cell state transitions by NOTCH1-REST transcriptional axis. World J Stem Cells 2026; In press
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Received |
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2026-01-04 08:28 |
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Peer-Review Started |
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2026-01-04 08:28 |
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First Decision by Editorial Office Director |
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2026-01-16 03:46 |
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Return for Revision |
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2026-01-16 03:46 |
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Revised |
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2026-03-31 06:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-15 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-15 07:00 |
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Articles in Press |
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2026-06-15 07:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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