Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	117654
Country	Nigeria

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Assessing hepatocellular carcinoma in Nigeria: A multicenter retrospective cohort review of prevalence, risk factors, and treatment outcomes
Manuscript Source	Invited Manuscript
All Author List	Yusuf Musa, Nasiru Altine Dankiri, Habib Tijjani Saleh, Chinwe Philomena Onyia, Lukman Olaitan Abdulkareem, Kenechukwu C Okonkwo, Fatimah Biade Abdulkareem, Rukayya Babale Shu'aibu, Abubakar Sadiq Aminu, Adamu Mohammad Ewa, Hafizu Zubairu Abdullahi, Adiri Winnifred Njideka, Hassan Ishaq Sunusi, Uchenna N Ijoma, Nduka Vitus Sunday, Evaristus Sunday Chukwudike, Uchenna F Okeke, Promise Udoka Asogwa, George Duke Mukoro, Muhammad Kabir Abdullahi, Emuobor A Odeghe, Chinenye Nwoko, Isa M Takwashe, Oluwatosin Oluwagbenga Oguntoye, Opeyemi Olubukola Owoseni, Aminat Oluwabukola Jimoh and Ganiyat Kikelomo Oyeleke
Funding Agency and Grant Number
Corresponding Author	Yusuf Musa, Chief Physician, Consultant, MD, Department of Internal Medicine, Federal Teaching Hospital Katsina, Murtala Muhammad Way, Opposite Jibia Road, Katsina 820101, Katsina, Nigeria. yusuf.musa@npmcn.edu.ng
Key Words	Hepatocellular carcinoma; Chronic hepatitis B virus; Chronic hepatitis C virus; Aflatoxin; Late presentation; Surgical resection; Locoregional therapy; Systemic therapy
Core Tip	This multicenter study reveals a 7.2% prevalence of hepatocellular carcinoma (HCC) across Nigeria, with most cases diagnosed at advanced stages. Hepatitis B remains the leading risk factor, compounded by lifestyle and environmental factors. Regional variations in prevalence and treatment patterns highlight disparities in healthcare access and infrastructure. Despite the availability of diverse treatment options, survival rates remain low, underscoring the urgent need for improved early detection, screening, and targeted public health strategies. These findings provide critical insights to guide policy development, enhance management protocols, and ultimately improve outcomes for patients with HCC in Nigeria.
Citation	Musa Y, Dankiri NA, Saleh HT, Onyia CP, Abdulkareem LO, Okonkwo KC, Abdulkareem FB, Shu'aibu RB, Aminu AS, Ewa AM, Abdullahi HZ, Njideka AW, Sunusi HI, Ijoma UN, Sunday NV, Chukwudike ES, Okeke UF, Asogwa PU, Mukoro GD, Abdullahi MK, Odeghe EA, Nwoko C, Takwashe IM, Oguntoye OO, Owoseni OO, Jimoh AO, Oyeleke GK. Assessing hepatocellular carcinoma in Nigeria: A multicenter retrospective cohort review of prevalence, risk factors, and treatment outcomes. World J Gastrointest Oncol 2026; In press

Received	2025-12-15 01:30
Peer-Review Started	2025-12-15 01:30
First Decision by Editorial Office Director	2025-12-26 09:52
Return for Revision	2025-12-26 09:52
Revised	2026-01-08 22:32
Publication Fee Transferred
Second Decision by Editor	2026-01-30 02:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-30 07:25
Articles in Press	2026-01-30 07:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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