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Publication Name World Journal of Diabetes
Manuscript ID 117665
Country China
Category Biology
Manuscript Type Editorial
Article Title Bridging tradition and innovation: Targeting ferroptosis opens a new traditional Chinese medicine dimension in diabetic wound therapy
Manuscript Source Invited Manuscript
All Author List Min Yang, Jing-Shun Lu, Guo-Dong Zhang, Ze-Wei He, Zeng-Gao Han, Chen-Yu Song and Kai-Yang Wang
Funding Agency and Grant Number
Corresponding Author Kai-Yang Wang, MD, Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600 Yishan Road, Shanghai 200233, China. ortho_wang@163.com
Key Words Diabetic foot ulcer; Ferroptosis; Traditional Chinese medicine; Nrf2 pathway; Wound healing; Iron metabolism
Core Tip Diabetic foot ulcer (DFU) is one of the most severe complications of diabetes mellitus, primarily due to its prolonged non-healing nature and high amputation rate. The pathogenesis of DFU is complex. In recent years, ferroptosis has been identified as a potential key pathological mechanism underlying this condition. Within this context, traditional Chinese medicine, with its multi-targeted intervention capabilities on both structural skin cells and inflammatory immune cells, has demonstrated promising therapeutic prospects in the management of DFU.
Citation Yang M, Lu JS, Zhang GD, He ZW, Han ZG, Song CY, Wang KY. Bridging tradition and innovation: Targeting ferroptosis opens a new traditional Chinese medicine dimension in diabetic wound therapy. World J Diabetes 2026; In press
Received
2025-12-15 01:53
Peer-Review Started
2025-12-16 09:43
First Decision by Editorial Office Director
2025-12-29 08:41
Return for Revision
2025-12-29 08:41
Revised
2026-01-10 05:47
Publication Fee Transferred
Second Decision by Editor
2026-02-02 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-02 09:36
Articles in Press
2026-02-02 09:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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